My Favorite Leaky Gut Trio

I promised I would highlight some powerful technologies for leaky gut that work well together when we introduced Anova Health MBM a few weeks ago.

In the past two months we have attended two conferences including the Gut Brain and Microbiome conferences in Florida. While much information on various aspects  of complex interactions were presented there were few innovative or outstanding products or protocols that excite me as much as the ones I will discuss here.

Our favorite technologies for the reinoculate and repair steps of the 4R program of remove, replace, reinoculate and repair that most of you know are:

1. Pharmax HLC or Genestra HMF human microflora strains
2. Anova Health MBM Proven Prebiotic Formulation
3. Anova Health AvinoCort for core SIgA support

There is overwhelming evidence that 4 human strain floras have the ability to reinoculate the upper intestinal track where others cannot. Chosen from over 600 human strains after years of research this consortium 4 found in products from Pharmax and sister company Genestra have proven themselves in several long term human trials unrivaled by any other probiotic strains. HLC and HMF Probiotics come in various strengths based on need. Pharmax HLC Replenish is my favorite for one to two week intensive small intestine reinoculation.

Human strain probiotics are the safest in the industry. Please be aware that many of the new “spore” based probiotics while hardly have not been proven SAFE in many instances and can actually be dangerous to certain individuals.  There have been 9 deaths from septicemia form spore based organisms. Human strains and many food derived probiotics have a track record for safety.

Once probiotic reinoculation is addressed I will often consider broader based multi strain formulas for additional benefits but this step of reinoculating the small intestine first is very important.

One of the major reasons people have difficulty maintaining a health intestinal mucosa is stress. Prolonged stress leads to the suppression of Secretory IgA or (SIgA) and the protection SIgA provides from pathogens.

Anova Health AvinoCort has been proven to reduce many aspects of stress in a number of ways. One of the mechanisms identified with the embryonic peptides contained in Anova Health AvinoCort works via elevation of 17‐ketosteroid levels in the adrenal glands, which improve anabolism through increased synthesis of androgens and a decrease in (the catabolic hormone) cortisol, which offer multiple health benefits including increased SIgA levels.

Apart from its benefits in adrenal hormone modulation AvinoCort also provides a plethora of oligopeptides, stem cells, and growth factors that help provide the raw materials for repair of gut and brain cellular material. Because of the many factors in AvinoCort, about 70% of individuals  tend to report better sleep, more stamina, improved mood levels and more mental clarity. Individuals report varying degrees of these felt benefits within 2-5 days. Blood tests confirm better adrenal functions and metabolic syndrome markers in about 60 days in the 30% of individuals who don’t necessarily feel AvinoCort’s wow factor.

Anova Health MBM is a novel and highly effective prebiotic without the downside of sugar/starch based inulin, FOS or GOS. MBM has proven to repair leaky gut and elongate intestinal villi in pathology photographs. No other prebiotic has been able to prove this.

The evolution of change and improvement in nutrient absorption by the intestinal epithelial cell during continuous administration of MBM has improved the biologically active ingredients (vitamins, macro- and microelements and vital amino acids, and enzymes) to significantly increase their absorption of nutrients by 70-80% compared to that of 7% in the case of ordinary wheat germ.

Multiple study trials have confirmed that the most important cells of the epithelium enterocytes of the small intestine mucosa, which are responsible for the normal process of absorption, were greatly enriched in the groups consuming MBM compared to the control groups. Further studies also confirmed that the prebiotic effects contribute to the renewal of intestinal cells.

Thanks to years of research and development of the proprietary enzymatic extraction technology, MBM is also free of fructans, gluten, and gliadin and contains a concentration of biologically active compounds such as benzoquinones and a rich amino-acid profile.

The synergistic effect of these biologically active compounds with vitamins and trace elements found in Anova Health MBM help nourish and sustain the growth and activity of over 300 species of beneficial bacteria in the gastro-intestinal microflora.

For additional information and questions please feel free to call our office at 864-408-8320.


  1. could not find any reference to the line mentioned in google search “proven SAFE in many instances and can actually be dangerous to certain individuals.”…..PLEASE EXPLAIN

    • Dr. Frank Charles says:

      Lori: Certain probiotics and especially some soil based organisms can harm immune compromised individuals. Seroyal who distributes Pharmax is a Canadian company and Health Canada is the equivalent to our FDA. They require this warning on any probiotic product. So this is a required blanket statement with all probiotic products in Canada but not the US. I can assure you that human strain probiotics have a long track record and many clinical studies in human proving them to be safe and highly effective. I cant say the same for all probiotics on the market.

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